Ki Summary

Reaction Details

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Target

C-C chemokine receptor type 5

Ligand

BDBM50488230

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_922573 (CHEMBL3077270)

IC50

47±n/a nM

Citation

TBA Med Chem Res22:1356-1364 (2013) Article

More Info.:

Get all data from this article, Assay Method

C-C chemokine receptor type 5

Name:

C-C chemokine receptor type 5

Synonyms:

Type:

Enzyme

Mol. Mass.:

40540.21

Organism:

Homo sapiens (Human)

Description:

P51681

Residue:

352

Sequence:

MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL

BDBM50488230

n/a

Name

BDBM50488230

Synonyms:

CHEMBL2281967

Type

Small organic molecule

Emp. Form.

C30H34BrClN2O3

Mol. Mass.

585.96

SMILES

Cc1cccc(C)c1NC(=O)NCC1(O)CCC(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1 |(55.12,-4.45,;56.45,-3.68,;56.45,-2.14,;57.79,-1.37,;59.12,-2.13,;59.12,-3.67,;60.45,-4.45,;57.77,-4.44,;57.77,-5.98,;56.44,-6.75,;55.11,-5.98,;56.44,-8.29,;57.77,-9.06,;57.77,-10.6,;59.1,-9.82,;59.11,-11.37,;59.11,-12.91,;57.77,-13.68,;57.78,-15.22,;56.44,-15.99,;55.11,-15.23,;53.78,-16,;52.45,-15.23,;53.78,-17.54,;55.11,-18.31,;56.45,-17.54,;57.78,-18.31,;57.79,-19.85,;59.12,-20.62,;59.12,-22.15,;60.45,-22.92,;61.78,-22.15,;63.12,-22.91,;61.78,-20.6,;60.44,-19.84,;56.44,-12.92,;56.44,-11.37,)|

Structure