| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50035651 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58344 (CHEMBL671959) |
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| IC50 | 115±n/a nM |
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| Citation |  Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Evaluation of cis- and trans-9- and 11-hydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridines as structurally rigid, selective D1 dopamine receptor ligands. J Med Chem38:318-27 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50035651 |
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| n/a |
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| Name | BDBM50035651 |
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| Synonyms: | (6aR,12bS)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridin-11-ol | CHEMBL111348 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19NO |
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| Mol. Mass. | 265.3496 |
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| SMILES | CN1Cc2ccccc2[C@H]2[C@H]1CCc1ccc(O)cc21 |
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| Structure | 
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