| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50492798 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_975879 (CHEMBL2415528) |
|---|
| Ki | 790±n/a nM |
|---|
| Citation |  Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579. Eur J Med Chem66:122-34 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50492798 |
|---|
| n/a |
|---|
| Name | BDBM50492798 |
|---|
| Synonyms: | CHEMBL2414355 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H27ClN4O |
|---|
| Mol. Mass. | 410.94 |
|---|
| SMILES | Clc1ccc(cc1)-n1cc(COCCCN2CCN(CC2)c2ccccc2)cn1 |
|---|
| Structure | 
|
|---|
Search and Browse
