| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metallo-beta-lactamase IMP-1 |
|---|
| Ligand | BDBM50493088 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_978383 (CHEMBL2424346) |
|---|
| IC50 | 1700±n/a nM |
|---|
| Citation |  Hiraiwa, Y; Morinaka, A; Fukushima, T; Kudo, T Metallo-?-lactamase inhibitory activity of 3-alkyloxy and 3-amino phthalic acid derivatives and their combination effect with carbapenem. Bioorg Med Chem21:5841-50 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metallo-beta-lactamase IMP-1 |
|---|
| Name: | Metallo-beta-lactamase IMP-1 |
|---|
| Synonyms: | Metallo beta-lactamase | Metallo-beta-lactamase IMP-1 | blaIMP-1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 14898.12 |
|---|
| Organism: | Pseudomonas aeruginosa |
|---|
| Description: | ChEMBL_116913 |
|---|
| Residue: | 133 |
|---|
| Sequence: | YVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISS
HFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPG
PGHTPDNVVVWLP
|
|
|
|---|
| BDBM50493088 |
|---|
| n/a |
|---|
| Name | BDBM50493088 |
|---|
| Synonyms: | CHEMBL2420935 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H16O5 |
|---|
| Mol. Mass. | 300.3059 |
|---|
| SMILES | OC(=O)c1cccc(OCCCc2ccccc2)c1C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
