| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor B |
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| Ligand | BDBM50039349 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_36643 (CHEMBL652353) |
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| Ki | 139±n/a nM |
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| Citation |  Nicolaï, E; Curé, G; Goyard, J; Kirchner, M; Teulon, JM; Versigny, A; Cazes, M; Caussade, F; Virone-Oddos, A; Cloarec, A Synthesis and SAR studies of novel triazolopyrimidine derivatives as potent, orally active angiotensin II receptor antagonists. J Med Chem37:2371-86 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor B |
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| Name: | Type-1 angiotensin II receptor B |
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| Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40929.44 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT1B 0 RAT::P29089 |
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| Residue: | 359 |
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| Sequence: | MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
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| BDBM50039349 |
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| n/a |
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| Name | BDBM50039349 |
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| Synonyms: | 5-Methyl-7-propyl-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonic acid methylamide | CHEMBL76359 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N9O2S |
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| Mol. Mass. | 503.579 |
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| SMILES | CCCc1nc(C)n2nc(nc2c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)S(=O)(=O)NC |
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| Structure | 
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