| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor B |
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| Ligand | BDBM50406795 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_36636 (CHEMBL652347) |
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| IC50 | 1.5±n/a nM |
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| Citation |  Mederski, WW; Dorsch, D; Bokel, HH; Beier, N; Lues, I; Schelling, P Non-peptide angiotensin II receptor antagonists: synthesis and biological activity of a series of novel 4,5-dihydro-4-oxo-3H-imidazo[4,5-c]pyridine derivatives. J Med Chem37:1632-45 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor B |
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| Name: | Type-1 angiotensin II receptor B |
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| Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40929.44 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT1B 0 RAT::P29089 |
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| Residue: | 359 |
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| Sequence: | MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
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| BDBM50406795 |
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| n/a |
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| Name | BDBM50406795 |
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| Synonyms: | Cozaar | LOSARTAN POTASSIUM |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22ClN6O |
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| Mol. Mass. | 421.903 |
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| SMILES | CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nn[n-]n1 |
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| Structure | 
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