| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50213103 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1283081 (CHEMBL3100637) |
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| Ki | 1828±n/a nM |
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| Citation |  Plazinska, A; Pajak, K; Rutkowska, E; Jimenez, L; Kozocas, J; Koolpe, G; Tanga, M; Toll, L; Wainer, IW; Jozwiak, K Comparative molecular field analysis of fenoterol derivatives interacting with an agonist-stabilized form of the ??-adrenergic receptor. Bioorg Med Chem22:234-46 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50213103 |
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| n/a |
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| Name | BDBM50213103 |
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| Synonyms: | (S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, Compound (S,R)-1 | US9492405, (S,R)-1 | US9492405, 30 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO4 |
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| Mol. Mass. | 303.3529 |
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| SMILES | C[C@H](Cc1ccc(O)cc1)NC[C@@H](O)c1cc(O)cc(O)c1 |
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| Structure | 
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