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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50495641 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1291677 (CHEMBL3119424) | ||
| Ki | 3093±n/a nM | ||
| Citation |  Lucchesi, V; Parkkari, T; Savinainen, JR; Malfitano, AM; Allarà, M; Bertini, S; Castelli, F; Del Carlo, S; Laezza, C; Ligresti, A; Saccomanni, G; Bifulco, M; Di Marzo, V; Macchia, M; Manera, C 1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor. Eur J Med Chem74:524-32 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
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| BDBM50495641 | |||
| n/a | |||
| Name | BDBM50495641 | ||
| Synonyms: | CHEMBL3114347 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H24N2O2 | ||
| Mol. Mass. | 324.4168 | ||
| SMILES | CC1CCC(CC1)NC(=O)c1cccnc1OCc1ccccc1 |(17.09,-54.87,;17.86,-53.54,;17.09,-52.2,;17.86,-50.86,;19.4,-50.87,;20.18,-52.2,;19.41,-53.54,;20.17,-49.53,;19.4,-48.18,;17.85,-48.18,;20.17,-46.85,;19.4,-45.51,;20.17,-44.17,;21.72,-44.17,;22.49,-45.51,;21.72,-46.85,;22.49,-48.18,;24.03,-48.18,;24.79,-49.52,;24.02,-50.84,;24.79,-52.17,;26.32,-52.17,;27.09,-50.83,;26.32,-49.51,)| | ||
| Structure | 
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