| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM50043046 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_35286 |
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| IC50 | 30±n/a nM |
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| Citation |  VanAtten, MK; Ensinger, CL; Chiu, AT; McCall, DE; Nguyen, TT; Wexler, RR; Timmermans, PB A novel series of selective, non-peptide inhibitors of angiotensin II binding to the AT2 site. J Med Chem36:3985-92 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41346.62 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT2 0 0::P35351 |
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| Residue: | 363 |
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| Sequence: | MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFA
VNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDT
FVS
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| BDBM50043046 |
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| n/a |
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| Name | BDBM50043046 |
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| Synonyms: | 2-Diphenylacetyl-6-phenyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid | CHEMBL128527 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H25NO3 |
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| Mol. Mass. | 447.5244 |
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| SMILES | OC(=O)C1Cc2cc(ccc2CN1C(=O)C(c1ccccc1)c1ccccc1)-c1ccccc1 |
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| Structure | 
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