| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Somatostatin receptor type 1 |
|---|
| Ligand | BDBM50496019 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1291911 (CHEMBL3124225) |
|---|
| IC50 | 33±n/a nM |
|---|
| Citation |  Tatsi, A; Maina, T; Cescato, R; Waser, B; Krenning, EP; de Jong, M; Cordopatis, P; Reubi, JC; Nock, BA [DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting. Eur J Med Chem73:30-7 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Somatostatin receptor type 1 |
|---|
| Name: | Somatostatin receptor type 1 |
|---|
| Synonyms: | SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42692.81 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P30872 |
|---|
| Residue: | 391 |
|---|
| Sequence: | MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL
ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL
RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG
VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC
LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD
DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS
RAYSVEDFQPENLESGGVFRNGTCTSRITTL
|
|
|
|---|
| BDBM50496019 |
|---|
| n/a |
|---|
| Name | BDBM50496019 |
|---|
| Synonyms: | CHEMBL3122123 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C92H131N21O24S2 |
|---|
| Mol. Mass. | 1979.281 |
|---|
| SMILES | [H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](CO)C(=O)NCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)CNC(=O)[C@H](C)NC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)[C@@H](C)O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
