| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A1 |
|---|
| Ligand | BDBM50045337 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_29016 |
|---|
| Ki | 65000±n/a nM |
|---|
| Citation |  Jacobson, KA; Shi, D; Gallo-Rodriguez, C; Manning, M; Müller, C; Daly, JW; Neumeyer, JL; Kiriasis, L; Pfleiderer, W Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. J Med Chem36:2639-44 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A1 |
|---|
| Name: | Adenosine receptor A1 |
|---|
| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36704.13 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 326 |
|---|
| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
|
|
|
|---|
| BDBM50045337 |
|---|
| n/a |
|---|
| Name | BDBM50045337 |
|---|
| Synonyms: | 8-Bromo-3-isobutyl-1-methyl-3,7-dihydro-purine-2,6-dione | CHEMBL314959 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H13BrN4O2 |
|---|
| Mol. Mass. | 301.14 |
|---|
| SMILES | CC(C)Cn1c2nc(Br)[nH]c2c(=O)n(C)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
