| Reaction Details |
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 | Report a problem with these data |
| Target | Chitinase |
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| Ligand | BDBM50498228 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1495717 (CHEMBL3578790) |
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| IC50 | 2080±n/a nM |
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| Citation |  Gooyit, M; Tricoche, N; Javor, S; Lustigman, S; Janda, KD Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting. ACS Med Chem Lett6:339-43 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chitinase |
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| Name: | Chitinase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55694.80 |
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| Organism: | Onchocerca volvulus |
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| Description: | ChEMBL_1369100 |
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| Residue: | 497 |
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| Sequence: | MRIGAMLIPFIILGNAIIAYGYVRGCYYTNWAQYRQGEGKFLPEDIPKGLCTHILYAFAK
VDQSGTSLPFEWNDEDTNWSKGMYSRVTKLKENDPEMKILLSYGGYNFGSSTFTAIRNRA
EKRKHFIKSAIAFLRKNKFDGFDFDWEYPIGMAQEYAKLVNEMKVAFVEEAKKSDSEQLL
LTAAVSAGKHTIDQSYNVQSLGENFDLLSLMSYDFHGSWEMNVDLHAKLHPTKGETSGTG
IFNTEFAANYWLSKGMPKQKIIIGIPTYGRGWTLRDSSKTTIGAEGISPSSPSTTNPAGG
TAAYWEICKYLKEGGKETIDEQGVGACMVQGSQWYGYDNEETIRMKMRWLKEKGYGGAFI
WTLDFDDFKGTSCGEGPYPLLSAINHELKGEATATTRSLRTTITQSSTIGSTKFETTTTA
SEITKNNKIKTTTIAVEPTGESSDIKCPESFGLFRHPNDCHLFIHCAHDHPYVKLCPPNT
FFNDKIKVCDHFGECDE
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| BDBM50498228 |
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| n/a |
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| Name | BDBM50498228 |
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| Synonyms: | CHEMBL3577758 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H20Cl2N2O |
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| Mol. Mass. | 447.356 |
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| SMILES | Cc1nccc2c3ccc(OCc4ccc(Cl)cc4)cc3n(Cc3ccc(Cl)cc3)c12 |
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| Structure | 
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