| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50498229 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1496710 (CHEMBL3579413) |
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| Ki | 0.006±n/a nM |
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| Citation |  Agniswamy, J; Louis, JM; Shen, CH; Yashchuk, S; Ghosh, AK; Weber, IT Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20. J Med Chem58:5088-95 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50498229 |
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| n/a |
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| Name | BDBM50498229 |
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| Synonyms: | CHEMBL3577575 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H35F2N3O7S |
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| Mol. Mass. | 583.645 |
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| SMILES | [H][C@@]12OC[C@H](OC(=O)N[C@@H](Cc3ccccc3)[C@H](O)CN(CC(C)C)S(=O)(=O)c3ccc(N)cc3)[C@]1([H])C(F)(F)CO2 |r| |
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| Structure | 
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