| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50047209 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29455 |
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| Ki | 6280±n/a nM |
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| Citation |  Jacobson, KA; Gallo-Rodriguez, C; Melman, N; Fischer, B; Maillard, M; van Bergen, A; van Galen, PJ; Karton, Y Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists. J Med Chem36:1333-42 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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|
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| BDBM50047209 |
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| n/a |
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| Name | BDBM50047209 |
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| Synonyms: | 8-{2-[4-(4-Amino-but-2-enyloxy)-3,5-dimethoxy-phenyl]-vinyl}-1,3,7-trimethyl-3,7-dihydro-purine-2,6-dione | CHEMBL283406 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N5O5 |
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| Mol. Mass. | 441.4803 |
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| SMILES | COc1cc(\C=C\c2nc3n(C)c(=O)n(C)c(=O)c3n2C)cc(OC)c1OC\C=C\CN |
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| Structure | 
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