| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50499699 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1543178 (CHEMBL3744902) |
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| Ki | >200000±n/a nM |
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| Citation |  Moas-Héloire, V; Renault, N; Batalha, V; Arias, AR; Marchivie, M; Yous, S; Deguine, N; Buée, L; Chavatte, P; Blum, D; Lopes, L; Melnyk, P; Agouridas, L Design and synthesis of fused tetrahydroisoquinoline-iminoimidazolines. Eur J Med Chem106:15-25 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50499699 |
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| n/a |
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| Name | BDBM50499699 |
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| Synonyms: | CHEMBL3740794 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H26Cl2N4O |
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| Mol. Mass. | 373.321 |
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| SMILES | Cl.Cl.[H][C@]12CN(CCN3CCOCC3)C(=N)N1Cc1ccccc1C2 |r| |
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| Structure | 
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