Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 1A | ||
Ligand | BDBM50048821 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_845 (CHEMBL615901) | ||
IC50 | 140±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 1A | |||
Name: | 5-hydroxytryptamine receptor 1A | ||
Synonyms: | 5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_RAT | 5ht1a | G-21 | Htr1a | Serotonin 1 (5-HT1) receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 46445.29 | ||
Organism: | Rattus norvegicus (rat) | ||
Description: | Binding assays were performed using rat hippocampal membranes. | ||
Residue: | 422 | ||
Sequence: |
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BDBM50048821 | |||
n/a | |||
Name | BDBM50048821 | ||
Synonyms: | 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-cyclohexyl]-2,3-dihydro-isoindol-1-one | CHEMBL41309 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H28N4OS | ||
Mol. Mass. | 432.581 | ||
SMILES | O=C1N(Cc2ccccc12)C1CCC(CC1)N1CCN(CC1)c1nsc2ccccc12 |(5.61,-11.3,;4.82,-12.63,;5.59,-14.05,;4.24,-15.07,;2.92,-14.27,;1.45,-14.71,;.31,-13.66,;.68,-12.16,;2.14,-11.71,;3.27,-12.75,;7.09,-14.4,;7.25,-15.93,;9.06,-16.06,;9.97,-16.91,;9.8,-15.39,;8.07,-15.29,;11.46,-17.3,;11.44,-15.77,;12.79,-15,;14.12,-15.77,;14.11,-17.31,;12.79,-18.08,;15.46,-15,;15.63,-13.48,;17.12,-13.15,;17.89,-14.5,;19.39,-14.81,;19.87,-16.27,;18.85,-17.42,;17.33,-17.1,;16.87,-15.63,)| | ||
Structure | ![]() |