| Reaction Details |
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 | Report a problem with these data |
| Target | Cytosolic purine 5'-nucleotidase |
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| Ligand | BDBM50500512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1544056 (CHEMBL3750564) |
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| Ki | 2780000±n/a nM |
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| Citation |  Marton, Z; Guillon, R; Krimm, I; Preeti, na; Rahimova, R; Egron, D; Jordheim, LP; Aghajari, N; Dumontet, C; Périgaud, C; Lionne, C; Peyrottes, S; Chaloin, L Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach. J Med Chem58:9680-96 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytosolic purine 5'-nucleotidase |
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| Name: | Cytosolic purine 5'-nucleotidase |
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| Synonyms: | 3.1.3.5 | 5NTC_HUMAN | NT5B | NT5C2 | NT5CP | PNT5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64964.00 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_110158 |
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| Residue: | 561 |
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| Sequence: | MSTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVY
KSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLV
CAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTS
CETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMK
EVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGT
VLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKS
KKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQ
RRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAA
HVLMPHESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLA
PQEITHCHDEDDDEEEEEEEE
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| BDBM50500512 |
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| n/a |
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| Name | BDBM50500512 |
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| Synonyms: | CHEMBL3746515 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13N5O |
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| Mol. Mass. | 315.3287 |
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| SMILES | O=C(Nc1ncnc2[nH]cnc12)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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