| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuromedin-U receptor 1 |
|---|
| Ligand | BDBM50500783 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1550246 (CHEMBL3760529) |
|---|
| EC50 | 0.575440±n/a nM |
|---|
| Citation |  Micewicz, ED; Bahattab, OS; Willars, GB; Waring, AJ; Navab, M; Whitelegge, JP; McBride, WH; Ruchala, P Small lipidated anti-obesity compounds derived from neuromedin U. Eur J Med Chem101:616-26 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuromedin-U receptor 1 |
|---|
| Name: | Neuromedin-U receptor 1 |
|---|
| Synonyms: | G-protein coupled receptor 66 | G-protein coupled receptor FM-3 | GPR66 | NMU-R1 | NMUR1 | NMUR1_HUMAN | Neuromedin-U receptor 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47370.42 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_103121 |
|---|
| Residue: | 426 |
|---|
| Sequence: | MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
QETDPS
|
|
|
|---|
| BDBM50500783 |
|---|
| n/a |
|---|
| Name | BDBM50500783 |
|---|
| Synonyms: | CHEMBL3759452 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C47H71N15O9 |
|---|
| Mol. Mass. | 990.1617 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
