| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50051669 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29636 (CHEMBL639743) |
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| Ki | 64±n/a nM |
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| Citation |  Müller, CE; Geis, U; Grahner, B; Lanzner, W; Eger, K Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists. J Med Chem39:2482-91 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50051669 |
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| n/a |
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| Name | BDBM50051669 |
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| Synonyms: | 2-Phenyl-9-((S)-1-phenyl-ethyl)-9H-pyrimido[4,5-b]indol-4-ylamine | 2-Phenyl-9-(1-phenyl-ethyl)-9H-1,3,9-triaza-fluoren-4-ylamine (APEPI) | CHEMBL309511 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20N4 |
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| Mol. Mass. | 364.4424 |
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| SMILES | C[C@@H](c1ccccc1)n1c2ccccc2c2c(N)nc(nc12)-c1ccccc1 |
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| Structure | 
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