| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM50052694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_152658 (CHEMBL761584) |
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| pH | 6.8±n/a |
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| Ki | 4400000±n/a nM |
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| Comments | extracted |
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| Citation |  Meara, JP; Rich, DH Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors. J Med Chem39:3357-66 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM50052694 |
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| n/a |
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| Name | BDBM50052694 |
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| Synonyms: | (2S,3R)-3-Hydroxymethyl-oxirane-2-carboxylic acid [(S)-3-methyl-1-(3-methyl-butylcarbamoyl)-butyl]-amide | CHEMBL112618 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H28N2O4 |
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| Mol. Mass. | 300.3938 |
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| SMILES | CC(C)CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H]1O[C@@H]1CO |
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| Structure | 
|
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