Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 1A | ||
Ligand | BDBM50001955 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1173 (CHEMBL615939) | ||
Ki | 296±n/a nM | ||
Citation | Hedberg, MH; Linnanen, T; Jansen, JM; Nordvall, G; Hjorth, S; Unelius, L; Johansson, AM 11-substituted (R)-aporphines: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions. J Med Chem39:3503-13 (1996) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 1A | |||
Name: | 5-hydroxytryptamine receptor 1A | ||
Synonyms: | 5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_RAT | 5ht1a | G-21 | Htr1a | Serotonin 1 (5-HT1) receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 46445.29 | ||
Organism: | Rattus norvegicus (rat) | ||
Description: | Binding assays were performed using rat hippocampal membranes. | ||
Residue: | 422 | ||
Sequence: |
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BDBM50001955 | |||
n/a | |||
Name | BDBM50001955 | ||
Synonyms: | (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO) | (Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine) | (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine) | (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine) | (apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine) | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine) | APOKYN | APOMORPHINE | APOMORPHINE HYDROCHLORIDE | APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | CHEMBL53 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H17NO2 | ||
Mol. Mass. | 267.3224 | ||
SMILES | CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| | ||
Structure |