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TargetD(2) dopamine receptor
LigandBDBM50054145
Substrate/Competitorn/a
Meas. Tech.ChEMBL_59317 (CHEMBL670211)
IC50 6550.0±n/a nM
Citation Comoy, CMarot, CPodona, TBaudin, MLMorin-Allory, LGuillaumet, GPfeiffer, BCaignard, DHRenard, PRettori, MCAdam, GGuardiola-Lemaitre, B 3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans] J Med Chem39:4285-98 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(2) dopamine receptor
Name:D(2) dopamine receptor
Synonyms:DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:50698.79
Organism:BOVINE
Description:P20288
Residue:444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFLKILHC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50054145
n/a
NameBDBM50054145
Synonyms:5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)] | CHEMBL422453
TypeSmall organic molecule
Emp. Form.C16H23NO2
Mol. Mass.261.3593
SMILESCCCN1CCCC11COc2cccc(OC)c2C1
Structure
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