| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 3 |
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| Ligand | BDBM50503789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1812147 (CHEMBL4311607) |
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| Kd | 33±n/a nM |
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| Citation |  Va?kevi?ien?, I; Paketuryt?, V; Pajanok, N; ?ukauskas, ?; Sapijanskait?, B; Kantminien?, K; Mickevi?ius, V; Zubrien?, A; Matulis, D Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases. Bioorg Med Chem27:322-337 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 3 |
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| Name: | Carbonic anhydrase 3 |
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| Synonyms: | CA-III | CA3 | CAH3_HUMAN | Carbonate dehydratase III | Carbonic Anhydrase III | Carbonic anhydrase | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III (CA III) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29562.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 260 |
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| Sequence: | MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL
NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL
VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP
SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL
VSNWRPPQPINNRVVRASFK
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| BDBM50503789 |
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| n/a |
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| Name | BDBM50503789 |
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| Synonyms: | CHEMBL4452277 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15ClN2O5S |
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| Mol. Mass. | 346.787 |
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| SMILES | Cc1cc(N2CC(CC2=O)C(O)=O)c(Cl)c(C)c1S(N)(=O)=O |
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| Structure | 
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