| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
|---|
| Ligand | BDBM50504116 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1813607 (CHEMBL4313181) |
|---|
| IC50 | 710±n/a nM |
|---|
| Citation |  El-Gamal, MI; Ullah, S; Zaraei, SO; Jalil, S; Zaib, S; Zaher, DM; Omar, HA; Anbar, HS; Pelletier, J; Sévigny, J; Iqbal, J Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. Eur J Med Chem181:0 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
|---|
| Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
|---|
| Synonyms: | Alkaline phosphodiesterase I | CD_antigen=CD203c | E-NPP 3 | ENPP3 | ENPP3_HUMAN | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | NPPase | Nucleotide pyrophosphatase | PD-Ibeta | PDNP3 | Phosphodiesterase I beta | Phosphodiesterase I/nucleotide pyrophosphatase 3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 100124.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_101240 |
|---|
| Residue: | 875 |
|---|
| Sequence: | MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFD
ASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCL
QRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTL
MPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS
SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS
TLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRN
LHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNS
EEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGG
GNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLN
HLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEI
TATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPT
VPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEE
FRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHY
FVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVR
DVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI
|
|
|
|---|
| BDBM50504116 |
|---|
| n/a |
|---|
| Name | BDBM50504116 |
|---|
| Synonyms: | CHEMBL4473374 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C48H51NO8S3 |
|---|
| Mol. Mass. | 866.115 |
|---|
| SMILES | CC(C)(C)c1ccc(cc1)S(=O)(=O)Oc1ccc(cc1)-c1sc2cc(OS(=O)(=O)c3ccc(cc3)C(C)(C)C)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
