| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50504135 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1813620 (CHEMBL4313194) |
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| Ki | 0.090000±n/a nM |
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| Citation |  Rusere, LN; Lockbaum, GJ; Lee, SK; Henes, M; Kosovrasti, K; Spielvogel, E; Nalivaika, EA; Swanstrom, R; Yilmaz, NK; Schiffer, CA; Ali, A HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J Med Chem62:8062-8079 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50504135 |
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| n/a |
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| Name | BDBM50504135 |
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| Synonyms: | CHEMBL4459766 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H40N2O9S |
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| Mol. Mass. | 592.701 |
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| SMILES | [H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(cc1)[C@@H](O)CO |r| |
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| Structure | 
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