| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50055735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62399 (CHEMBL872888) |
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| Ki | 270±n/a nM |
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| Citation |  Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD 3-[[(4-Aryl-1-piperazinyl)alkyl]cyclohexyl]-1H-indoles as dopamine D2 partial agonists and autoreceptor agonists. J Med Chem40:250-9 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50055735 |
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| n/a |
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| Name | BDBM50055735 |
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| Synonyms: | 3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohex-1-enyl}-1H-indole | CHEMBL87481 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30N4 |
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| Mol. Mass. | 386.5325 |
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| SMILES | C(CN1CCN(CC1)c1ccccn1)C1CCC(=CC1)c1c[nH]c2ccccc12 |c:19| |
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| Structure | 
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