| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 1 |
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| Ligand | BDBM50056163 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48699 (CHEMBL657992) |
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| IC50 | 800±n/a nM |
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| Citation |  Havlícek, L; Hanus, J; Veselý, J; Leclerc, S; Meijer, L; Shaw, G; Strnad, M Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds. J Med Chem40:408-12 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 1 |
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| Name: | Cyclin-dependent kinase 1 |
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| Synonyms: | CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 34101.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06493 |
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| Residue: | 297 |
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| Sequence: | MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
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| BDBM50056163 |
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| n/a |
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| Name | BDBM50056163 |
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| Synonyms: | (S)-2-(6-(benzylamino)-9-isopropyl-9H-purin-2-ylamino)butan-1-ol | (S)-2-(6-Benzylamino-9-isopropyl-9H-purin-2-ylamino)-butan-1-ol | CHEMBL133342 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26N6O |
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| Mol. Mass. | 354.4493 |
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| SMILES | CC[C@@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1 |r| |
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| Structure | 
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