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TargetAmine oxidase [flavin-containing] B
LigandBDBM50057303
Substrate/Competitorn/a
Meas. Tech.ChEMBL_123607 (CHEMBL734187)
Ki 260000±n/a nM
Citation Zhou, JJ; Li, J; Upadhyaya, S; Eaton, PE; Silverman, RB 4-substituted cubylcarbinylamines: a new class of mechanism-based monoamine oxidase B inactivators. J Med Chem40:1165-8 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B
Type:PROTEIN
Mol. Mass.:58428.94
Organism:Bos taurus
Description:ChEMBL_1501478
Residue:520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWR
TMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEV
SALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQ
TGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVY
YKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEER
LKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTT
FLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
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BDBM50057303
n/a
NameBDBM50057303
Synonyms:C-(6-Cyclopropyl-cuban-3-yl)-methylamine | CHEMBL16608
TypeSmall organic molecule
Emp. Form.C12H15N
Mol. Mass.173.2542
SMILESNCC12C3C4C1C1C2C3C41C1CC1 |(14.18,-3.72,;12.92,-2.86,;11.53,-3.52,;9.59,-3.4,;9.34,-5.33,;11.28,-5.44,;10.76,-4.93,;11.02,-3,;9.09,-2.88,;8.84,-4.82,;7.47,-5.49,;5.93,-5.39,;6.61,-6.77,)|
Structure
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