| Reaction Details |
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 | Report a problem with these data |
| Target | Sulfhydryl oxidase 1 |
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| Ligand | BDBM34233 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1823889 (CHEMBL4323653) |
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| IC50 | 5400±n/a nM |
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| Citation |  Ruberte, AC; Sanmartin, C; Aydillo, C; Sharma, AK; Plano, D Development and Therapeutic Potential of Selenazo Compounds. J Med Chem63:1473-1489 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sulfhydryl oxidase 1 |
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| Name: | Sulfhydryl oxidase 1 |
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| Synonyms: | 1.8.3.2 | QSCN6 | QSOX1 | QSOX1_HUMAN | Quiescin Q6 | Sulfhydryl oxidase 1 | hQSOX |
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| Type: | PROTEIN |
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| Mol. Mass.: | 82602.44 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118867 |
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| Residue: | 747 |
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| Sequence: | MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA
WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT
VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF
ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL
FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY
MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR
QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR
QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS
HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI
ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG
PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN
RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS
FMGLLAMYTYFQAKIRALKGHAGHPAA
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| BDBM34233 |
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| n/a |
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| Name | BDBM34233 |
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| Synonyms: | 2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen) | 2-phenyl-1,2-benzisoselazol-3(2H)-one | 2-phenyl-1,2-benzoselenazol-3-one | 2-phenylbenzo[d][1,2]selenazol-3(2H)-one | CHEMBL51085 | EBSELEN | Ebselen (C5) | MLS000028488 | SMR000058445 | cid_3194 | med.21724, Compound 153 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9NOSe |
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| Mol. Mass. | 274.18 |
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| SMILES | O=c1n([se]c2ccccc12)-c1ccccc1 |
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| Structure | 
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