Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50058022 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_202076 (CHEMBL811508) |
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Ki | 1.7±n/a nM |
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Citation | Waterhouse, RN; Mardon, K; Giles, KM; Collier, TL; O'Brien, JC Halogenated 4-(phenoxymethyl)piperidines as potential radiolabeled probes for sigma-1 receptors: in vivo evaluation of [123I]-1-(iodopropen-2-yl)-4-[(4-cyanophenoxy)methyl]pip eri dine. J Med Chem40:1657-67 (1997) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50058022 |
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n/a |
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Name | BDBM50058022 |
Synonyms: | 1-(3-Fluoro-propyl)-4-pentafluorophenyloxymethyl-piperidine | CHEMBL44304 |
Type | Small organic molecule |
Emp. Form. | C15H17F6NO |
Mol. Mass. | 341.292 |
SMILES | FCCCN1CCC(COc2c(F)c(F)c(F)c(F)c2F)CC1 |
Structure |
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