| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2b |
|---|
| Ligand | BDBM50058225 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_32913 (CHEMBL645901) |
|---|
| Ki | 177±n/a nM |
|---|
| Citation |  Glase, SA; Akunne, HC; Georgic, LM; Heffner, TG; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wise, LD Substituted [(4-phenylpiperazinyl)-methyl]benzamides: selective dopamine D4 agonists. J Med Chem40:1771-2 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2b |
|---|
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_RAT | Adenosine receptor | Adora2b |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36378.84 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_32934 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFA
IPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGT
RARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYS
FHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
|
|
|
|---|
| BDBM50058225 |
|---|
| n/a |
|---|
| Name | BDBM50058225 |
|---|
| Synonyms: | CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide | N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide | PD-168077 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H22N4O |
|---|
| Mol. Mass. | 334.4149 |
|---|
| SMILES | Cc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1C#N |
|---|
| Structure | 
|
|---|
Search and Browse
