| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 11 |
|---|
| Ligand | BDBM50507255 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1829490 (CHEMBL4329364) |
|---|
| IC50 | 1020±n/a nM |
|---|
| Citation |  Fleming, CL; Natoli, A; Schreuders, J; Devlin, M; Yoganantharajah, P; Gibert, Y; Leslie, KG; New, EJ; Ashton, TD; Pfeffer, FM Highly fluorescent and HDAC6 selective scriptaid analogues. Eur J Med Chem162:321-333 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 11 |
|---|
| Name: | Histone deacetylase 11 |
|---|
| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 39187.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q96DB2 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
|
|
|
|---|
| BDBM50507255 |
|---|
| n/a |
|---|
| Name | BDBM50507255 |
|---|
| Synonyms: | CHEMBL4465218 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H17N3O6 |
|---|
| Mol. Mass. | 371.3441 |
|---|
| SMILES | ONC(=O)CCCCCN1C(=O)c2cccc3c(ccc(C1=O)c23)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
