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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cytochrome P450 1B1 | ||
| Ligand | BDBM50203126 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1830572 (CHEMBL4330580) | ||
| IC50 | 94±n/a nM | ||
| Citation |  Mohd Siddique, MU; Barbhuiya, TK; Sinha, BN; Jayaprakash, V Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1. Eur J Med Chem163:28-36 (2019) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cytochrome P450 1B1 | |||
| Name: | Cytochrome P450 1B1 | ||
| Synonyms: | CP1B1_HUMAN | CYP1B1 | CYPIB1 | Cytochrome P450 1B1 (CYP1B1) | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 60861.81 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1474523 | ||
| Residue: | 543 | ||
| Sequence: |
| ||
| BDBM50203126 | |||
| n/a | |||
| Name | BDBM50203126 | ||
| Synonyms: | 3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrido[2,1-a]isoquinolin-5-ylium | 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium | 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium chloride | 9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium; chloride | BERBERINE | Berberinechloride | CHEMBL12089 | berberine dimer | cid_12456 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H18NO4 | ||
| Mol. Mass. | 336.3607 | ||
| SMILES | COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC | ||
| Structure | 
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