| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50508789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1834345 (CHEMBL4334353) |
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| IC50 | 60±n/a nM |
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| Citation |  Pribut, N; Basson, AE; van Otterlo, WAL; Liotta, DC; Pelly, SC Aryl Substituted Benzimidazolones as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. ACS Med Chem Lett10:196-202 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50508789 |
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| n/a |
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| Name | BDBM50508789 |
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| Synonyms: | CHEMBL3775346 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22ClNO2S |
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| Mol. Mass. | 387.923 |
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| SMILES | CCOC(=O)c1[nH]c2ccc(Cl)cc2c1C(SC)c1cc(C)cc(C)c1 |
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| Structure | 
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