Reaction Details |
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Target | Translocator protein |
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Ligand | BDBM50509036 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1837171 (CHEMBL4337304) |
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Ki | 447±n/a nM |
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Citation | Cheng, HWA; Sokias, R; Werry, EL; Ittner, LM; Reekie, TA; Du, J; Gao, Q; Hibbs, DE; Kassiou, M First Nondiscriminating Translocator Protein Ligands Produced from a Carbazole Scaffold. J Med Chem62:8235-8248 (2019) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Translocator protein |
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Name: | Translocator protein |
Synonyms: | BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN |
Type: | Enzyme |
Mol. Mass.: | 18834.74 |
Organism: | Homo sapiens (Human) |
Description: | P30536 |
Residue: | 169 |
Sequence: | MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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BDBM50509036 |
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n/a |
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Name | BDBM50509036 |
Synonyms: | CHEMBL4532562 |
Type | Small organic molecule |
Emp. Form. | C31H30N2O3 |
Mol. Mass. | 478.5815 |
SMILES | CCN(Cc1cccc(OC)c1)C(=O)Cn1c2ccccc2c2cc(ccc12)-c1ccc(OC)cc1 |
Structure |
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