| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50069019 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_58646 |
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| Ki | 11±n/a nM |
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| Citation |  Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP Azepinoindole derivatives with high affinity for brain dopamine and serotonin receptors. Bioorg Med Chem Lett8:983-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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|
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| BDBM50069019 |
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| n/a |
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| Name | BDBM50069019 |
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| Synonyms: | 7-Chloro-1-(4-fluoro-phenyl)-8,9-dimethoxy-4-methyl-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole | CHEMBL176356 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22ClFN2O2 |
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| Mol. Mass. | 376.852 |
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| SMILES | COc1c2N(CC3CN(C)CCc(c23)c(Cl)c1OC)c1ccc(F)cc1 |
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| Structure | 
|
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