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TargetInositol hexakisphosphate kinase 2
LigandBDBM76563
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1868987 (CHEMBL4370053)
IC50 12900±n/a nM
Citation Gu, C; Stashko, MA; Puhl-Rubio, AC; Chakraborty, M; Chakraborty, A; Frye, SV; Pearce, KH; Wang, X; Shears, SB; Wang, H Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis. J Med Chem62:1443-1454 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Inositol hexakisphosphate kinase 2
Name:Inositol hexakisphosphate kinase 2
Synonyms:2.7.4.- | IHPK2 | IP6K2 | IP6K2_HUMAN | Inositol hexakisphosphate kinase 2 | InsP6 kinase 2 | InsP6K2 | P(i)-uptake stimulator | PiUS
Type:PROTEIN
Mol. Mass.:49188.38
Organism:Homo sapiens
Description:ChEMBL_119238
Residue:426
Sequence:
MSPAFRAMDVEPRAKGVLLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMR
KFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHH
VLETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVEKKGNISSQLKHYNPWS
MKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQ
IRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLR
RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKERPEVVLDSDAEDLEDLSEESA
DESAGAYAYKPIGASSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI
SEESGE
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BDBM76563
n/a
NameBDBM76563
Synonyms:2-(4-hydroxyphenyl)-6-oxidanyl-chromen-4-one | 6-hydroxy-2-(4-hydroxyphenyl)-1-benzopyran-4-one | 6-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 6-hydroxy-2-(4-hydroxyphenyl)chromen-4-one | 6-hydroxy-2-(4-hydroxyphenyl)chromone | MLS001049030 | SMR000024483 | cid_182362
TypeSmall organic molecule
Emp. Form.C15H10O4
Mol. Mass.254.2375
SMILESOc1ccc(cc1)-c1cc(=O)c2cc(O)ccc2o1
Structure
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