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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Estrogen receptor beta | ||
| Ligand | BDBM50517936 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1870094 (CHEMBL4371261) | ||
| EC50 | 40±n/a nM | ||
| Citation |  Hanson, AM; Perera, KLIS; Kim, J; Pandey, RK; Sweeney, N; Lu, X; Imhoff, A; Mackinnon, AC; Wargolet, AJ; Van Hart, RM; Frick, KM; Donaldson, WA; Sem, DS A-C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions. J Med Chem61:4720-4738 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Estrogen receptor beta | |||
| Name: | Estrogen receptor beta | ||
| Synonyms: | ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta | ||
| Type: | Protein | ||
| Mol. Mass.: | 59238.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q92731 | ||
| Residue: | 530 | ||
| Sequence: |
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| BDBM50517936 | |||
| n/a | |||
| Name | BDBM50517936 | ||
| Synonyms: | CHEMBL4453541 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C13H18O | ||
| Mol. Mass. | 190.2814 | ||
| SMILES | CC1CCC(CC1)c1ccc(O)cc1 |(29.12,-19.6,;27.58,-19.59,;26.8,-20.92,;25.27,-20.92,;24.5,-19.58,;25.27,-18.25,;26.81,-18.26,;22.96,-19.58,;22.19,-18.25,;20.65,-18.25,;19.88,-19.58,;18.34,-19.58,;20.66,-20.92,;22.2,-20.91,)| | ||
| Structure | 
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