Reaction Details |
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Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Ligand | BDBM50518734 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1872186 (CHEMBL4373353) |
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Ki | 1370±n/a nM |
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Citation | Ieda, N; Itoh, K; Inoue, Y; Izumiya, Y; Kawaguchi, M; Miyata, N; Nakagawa, H An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity. Bioorg Med Chem Lett29:353-356 (2019) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Type: | PROTEIN |
Mol. Mass.: | 18248.11 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1502595 |
Residue: | 163 |
Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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BDBM50518734 |
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n/a |
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Name | BDBM50518734 |
Synonyms: | CHEMBL4467081 |
Type | Small organic molecule |
Emp. Form. | C22H24N2O5 |
Mol. Mass. | 396.4364 |
SMILES | OC(=O)[C@H](CCC(=O)N1CCOCC1)NC(=O)\C=C\c1ccc2ccccc2c1 |r| |
Structure |
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