| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50073025 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_33748 (CHEMBL647825) |
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| Ki | 1.1±n/a nM |
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| Citation |  Barlocco, D; Cignarella, G; Montesano, F; Leonardi, A; Mella, M; Toma, L Novel adrenoceptor antagonists with a tricyclic pyrrolodipyridazine skeleton. J Med Chem42:173-7 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 51511.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35348 |
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| Residue: | 466 |
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| Sequence: | MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
APAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTL
HPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCT
TARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLSENGEEV
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| BDBM50073025 |
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| n/a |
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| Name | BDBM50073025 |
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| Synonyms: | 8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethylamino}-6-methyl-6H-1,6,7,9a-tetraaza-fluoren-5-one | CHEMBL301078 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26ClN7O2 |
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| Mol. Mass. | 467.951 |
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| SMILES | COc1ccccc1N1CCN(CCNc2ccc3c4c(cn3n2)c(Cl)nn(C)c4=O)CC1 |
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| Structure | 
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