| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
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| Ligand | BDBM50073028 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32458 (CHEMBL643574) |
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| Ki | 6.59±n/a nM |
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| Citation |  Barlocco, D; Cignarella, G; Montesano, F; Leonardi, A; Mella, M; Toma, L Novel adrenoceptor antagonists with a tricyclic pyrrolodipyridazine skeleton. J Med Chem42:173-7 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1D adrenergic receptor |
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| Name: | Alpha-1D adrenergic receptor |
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| Synonyms: | ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60485.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | adrenergic Alpha1D ADRA1D HUMAN::P25100 |
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| Residue: | 572 |
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| Sequence: | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
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| BDBM50073028 |
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| n/a |
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| Name | BDBM50073028 |
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| Synonyms: | 8-Chloro-6-methyl-2-[2-(4-phenyl-piperazin-1-yl)-ethylamino]-6H-1,6,7,9a-tetraaza-fluoren-5-one | CHEMBL51074 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24ClN7O |
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| Mol. Mass. | 437.925 |
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| SMILES | Cn1nc(Cl)c2cn3nc(NCCN4CCN(CC4)c4ccccc4)ccc3c2c1=O |
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| Structure | 
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