Reaction Details | |||
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Target | Induced myeloid leukemia cell differentiation protein Mcl-1 | ||
Ligand | BDBM50519027 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1873795 (CHEMBL4375084) | ||
Ki | 24000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Induced myeloid leukemia cell differentiation protein Mcl-1 | |||
Name: | Induced myeloid leukemia cell differentiation protein Mcl-1 | ||
Synonyms: | BCL2L3 | Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | MCL1 | MCL1_HUMAN | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT | ||
Type: | Membrane; Single-pass membrane protein | ||
Mol. Mass.: | 37332.87 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q07820 | ||
Residue: | 350 | ||
Sequence: |
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BDBM50519027 | |||
n/a | |||
Name | BDBM50519027 | ||
Synonyms: | CHEMBL4547333 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H23N3O3S | ||
Mol. Mass. | 433.523 | ||
SMILES | CCc1sc2ncnc(N[C@H](C)C(O)=O)c2c1-c1ccccc1OCc1ccccc1 |r,wU:10.10,(33.92,-28.48,;33.15,-27.15,;31.61,-27.15,;30.71,-28.4,;29.24,-27.92,;27.91,-28.7,;26.57,-27.93,;26.57,-26.39,;27.9,-25.62,;27.9,-24.08,;26.56,-23.31,;26.55,-21.77,;25.23,-24.08,;23.89,-23.32,;25.23,-25.62,;29.24,-26.38,;30.71,-25.9,;31.18,-24.44,;30.15,-23.3,;30.62,-21.84,;32.13,-21.51,;33.16,-22.65,;32.69,-24.12,;33.72,-25.27,;35.23,-24.95,;36.26,-26.09,;35.78,-27.55,;36.81,-28.7,;38.32,-28.38,;38.79,-26.9,;37.76,-25.76,)| | ||
Structure | ![]() |