| Reaction Details |
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 | Report a problem with these data |
| Target | Hypoxanthine-guanine phosphoribosyltransferase |
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| Ligand | BDBM50519492 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1875757 (CHEMBL4377151) |
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| Ki | 250±n/a nM |
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| Citation |  Cheviet, T; Lefebvre-Tournier, I; Wein, S; Peyrottes, S Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues. J Med Chem62:8365-8391 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hypoxanthine-guanine phosphoribosyltransferase |
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| Name: | Hypoxanthine-guanine phosphoribosyltransferase |
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| Synonyms: | HGPRT | HGPRTase | HPRT | HPRT1 | HPRT_HUMAN | Hypoxanthine-guanine phosphoribosyltransferase | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) |
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| Type: | Protein |
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| Mol. Mass.: | 24579.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00492 |
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| Residue: | 218 |
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| Sequence: | MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
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| BDBM50519492 |
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| n/a |
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| Name | BDBM50519492 |
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| Synonyms: | CHEMBL1233663 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H15N4O7P |
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| Mol. Mass. | 346.2332 |
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| SMILES | O[C@@H]1[C@@H](COP(O)(O)=O)N[C@H]([C@@H]1O)c1c[nH]c2c1nc[nH]c2=O |r| |
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| Structure | 
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