| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM22925 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1875739 (CHEMBL4377133) |
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| Ki | 8.2±n/a nM |
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| Citation |  Cheviet, T; Lefebvre-Tournier, I; Wein, S; Peyrottes, S Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues. J Med Chem62:8365-8391 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | 3.5.4.4 | Adenosine deaminase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42457.37 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_119120 |
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| Residue: | 367 |
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| Sequence: | MNCKNMDTSYEIINYLTKDELDIDLSCMDKKERYKIWKRLPKCELHCHLDVCFSVDFFLN
VIRKYNIQPNMSDEEIIDYYLFSKPGKSLDEFVEKALRLTDIYIDYTVVEDLAKHAVFNK
YKEGVVLMEFRYSPSFMSFKHNLDKDLIHEAIVKGLNEAVALLEYKIQVGLLCTGDGGLS
HERMKEAAEFCIKHKKDFVGYDHAGHEVDLKPFKDIFDNIREEGISLSVHAGEDVSIPNL
NSLYTAINLLHVKRIGHGIRVSESQELIDLVKEKDILLEVCPISNVLLNNVKSMDTHPIR
MLYDAGVKVSVNSDDPGMFLTNITDNYEELYTHLNFTLADFMKMNLWAVQKSFVDPDIKN
KIISKYF
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| BDBM22925 |
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| n/a |
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| Name | BDBM22925 |
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| Synonyms: | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H,6H,7H,8H-imidazo[4,5-d][1,3]diazepin-8-ol | Covidarabine | Deoxycoformycin | Nipent | Pentostatin |
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| Type | Nucleoside or nucleotide |
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| Emp. Form. | C11H16N4O4 |
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| Mol. Mass. | 268.2691 |
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| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CNC=Nc12 |c:17| |
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| Structure | 
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