| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Ligand | BDBM50074941 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212262 |
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| IC50 | 50.0±n/a nM |
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| Citation |  Chen, MH; Steiner, MG; de Laszlo, SE; Patchett, AA; Anderson, MS; Hyland, SA; Onishi, HR; Silver, LL; Raetz, CR Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis. Bioorg Med Chem Lett9:313-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Name: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Synonyms: | LPXC_ECOLI | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC) | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LxpC) | UDP-3-O-acyl-GlcNAc deacetylase | asmB | envA | lpxC |
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| Type: | Enzyme |
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| Mol. Mass.: | 33952.00 |
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| Organism: | Escherichia coli |
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| Description: | P0A725 |
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| Residue: | 305 |
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| Sequence: | MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDT
MLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGI
DELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSAD
AFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKM
LDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAP
SAVLA
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| BDBM50074941 |
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| n/a |
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| Name | BDBM50074941 |
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| Synonyms: | (R)-2-(3-Propyl-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid hydroxyamide | CHEMBL324231 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N2O3 |
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| Mol. Mass. | 248.2777 |
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| SMILES | CCCc1cccc(c1)C1=N[C@H](CO1)C(=O)NO |t:10| |
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| Structure | 
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