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TargetSigma intracellular receptor 2
LigandBDBM50523091
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1888982 (CHEMBL4390736)
Ki 2.2±n/a nM
Citation Al-Ghanim, LZhu, XYAsong, GAblordeppey, SY SYA 013 analogs as moderately selective sigma-2 (? Bioorg Med Chem27:2421-2426 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma intracellular receptor 2
Name:Sigma intracellular receptor 2
Synonyms:MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:Protein
Mol. Mass.:20857.20
Organism:Homo sapiens (Human)
Description:Q5BJF2
Residue:176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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BDBM50523091
n/a
NameBDBM50523091
Synonyms:CHEMBL4577233
TypeSmall organic molecule
Emp. Form.C19H23ClFN3S
Mol. Mass.379.922
SMILESFc1ccc(SCCCN2CCCN(CC2)c2ccc(Cl)cn2)cc1
Structure
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