| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50523359 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1890164 (CHEMBL4391918) |
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| Ki | 112±n/a nM |
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| Citation |  Del Bello, F; Bonifazi, A; Giorgioni, G; Quaglia, W; Amantini, C; Morelli, MB; Santoni, G; Battiti, FO; Vistoli, G; Cilia, A; Piergentili, A Chemical manipulations on the 1,4-dioxane ring of 5-HT Eur J Med Chem168:461-473 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50523359 |
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| n/a |
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| Name | BDBM50523359 |
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| Synonyms: | CHEMBL4466677 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H32N2O3 |
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| Mol. Mass. | 444.5653 |
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| SMILES | COc1ccccc1N1CCN(CC2COCC(O2)(c2ccccc2)c2ccccc2)CC1 |
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| Structure | 
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