| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(3) dopamine receptor |
|---|
| Ligand | BDBM50523474 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1890415 (CHEMBL4392169) |
|---|
| Ki | 1246±n/a nM |
|---|
| Citation |  Keck, TM; Free, RB; Day, MM; Brown, SL; Maddaluna, MS; Fountain, G; Cooper, C; Fallon, B; Holmes, M; Stang, CT; Burkhardt, R; Bonifazi, A; Ellenberger, MP; Newman, AH; Sibley, DR; Wu, C; Boateng, CA Dopamine D J Med Chem62:3722-3740 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(3) dopamine receptor |
|---|
| Name: | D(3) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 44243.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 400 |
|---|
| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
|
|
|
|---|
| BDBM50523474 |
|---|
| n/a |
|---|
| Name | BDBM50523474 |
|---|
| Synonyms: | CHEMBL4473652 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H25N3O |
|---|
| Mol. Mass. | 359.4641 |
|---|
| SMILES | Cc1cccc(NC(=O)CN2CCN(CC2)c2cccc3ccccc23)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
