| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50078786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_38319 |
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| IC50 | 530±n/a nM |
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| Citation |  Mathvink, RJ; Barritta, AM; Candelore, MR; Cascieri, MA; Deng, L; Tota, L; Strader, CD; Wyvratt, MJ; Fisher, MH; Weber, AE Potent, elective human beta3 adrenergic receptor agonists containing a substituted indoline-5-sulfonamide pharmacophore. Bioorg Med Chem Lett9:1869-74 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50078786 |
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| n/a |
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| Name | BDBM50078786 |
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| Synonyms: | 1-(4-octylpyrimidin-2-yl)-N-phenyl-2,3-dihydro-1H-indole-5-sulfonamide | CHEMBL53359 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32N4O2S |
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| Mol. Mass. | 464.623 |
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| SMILES | CCCCCCCCc1ccnc(n1)N1CCc2cc(ccc12)S(=O)(=O)Nc1ccccc1 |
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| Structure | 
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