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TargetVesicular acetylcholine transporter
LigandBDBM50079280
Substrate/Competitorn/a
Meas. Tech.ChEMBL_213559 (CHEMBL817829)
Ki 5.2±n/a nM
Citation Efange, SMKhare, ABMach, RHParsons, SM Hydroxylated decahydroquinolines as ligands for the vesicular acetylcholine transporter: synthesis and biological evaluation. J Med Chem42:2862-9 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Vesicular acetylcholine transporter
Name:Vesicular acetylcholine transporter
Synonyms:SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN
Type:PROTEIN
Mol. Mass.:56900.67
Organism:Homo sapiens (Human)
Description:ChEMBL_1507628
Residue:532
Sequence:
MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
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  Blast E-value cutoff:
BDBM50079280
n/a
NameBDBM50079280
Synonyms:(4aR,6R,7R,8aR)-1-(3-Iodo-benzyl)-6-(4-phenyl-piperidin-1-yl)-decahydro-quinolin-7-ol | CHEMBL330386 | trans-trans-1-(3-iodobenzyl)-6-(4-phenylpiperidin-1-yl)-decahydroquinolin-7-ol
TypeSmall organic molecule
Emp. Form.C27H35IN2O
Mol. Mass.530.4841
SMILESO[C@@H]1C[C@@H]2[C@H](CCCN2Cc2cccc(I)c2)C[C@H]1N1CCC(CC1)c1ccccc1
Structure
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